Rotator Cuff Injuries: Surgery or Stem Cell Therapy? What the Evidence Says

Man holding his injured arm

The short answer. A rotator cuff tear is a tear in one of the tendons that cover the head of the upper arm bone and help you lift and rotate your arm, and most people improve without surgery1,2. Surgery is more often considered after a recent injury, for a large tear, or when pain and weakness last despite therapy1. Platelet-rich plasma (PRP) and bone marrow concentrate are also used, and studies have found fewer re-tears when either is added to a surgical repair, and greater improvement in pain and function after bone marrow concentrate injections than with a home exercise program3,4,5.

What is a rotator cuff tear?

The rotator cuff is a group of four muscles whose tendons form a covering around the head of the upper arm bone (humerus), attaching it to the shoulder blade1. In most tears the tendon is torn away from the bone, most often the supraspinatus tendon on top of the shoulder. The American Academy of Orthopaedic Surgeons (AAOS) estimates that almost 2 million people in the US see a doctor each year for rotator cuff tears1.

A fall on an outstretched arm or a jerking lift can tear the cuff, but most tears come from the tendon wearing down slowly over time1. When 664 residents of one Japanese village had shoulder ultrasounds, 22.1% had a full-thickness tear, rising from none in people in their 20s to 40s to 36.6% in their 80s, and about two-thirds of the tears caused no symptoms6. A pooled review of 30 studies and 6,112 shoulders called rotator cuff degeneration a common part of normal aging, common enough that it can be hard to tell whether a tear seen on a scan is causing a person's symptoms7.

Partial vs full-thickness rotator cuff tear: what is the difference?

AAOS describes the types this way1:

  • Partial tear. The tear goes only partway through the thickness of the tendon. The tendon is still attached to the bone, but it is thinner than normal.
  • Full-thickness tear. Part of the tendon is detached from the bone. When only a small part is detached it is called a full-thickness incomplete tear; when the tendon is completely detached it is a full-thickness complete tear, which leaves essentially a hole in the tendon.

Tears generally start as wear inside the tendon and progress from partial to full thickness, though not every tear progresses or causes symptoms8. For partial tears, conservative treatment is often the first line for most patients; the decision to operate depends on factors such as age, arm dominance, cause, activity level, and the thickness and location of the tear9.

What does a torn rotator cuff feel like?

The most common symptoms, according to AAOS, are1:

  • pain at rest and at night, especially when lying on the affected shoulder
  • pain when lifting and lowering the arm, or with specific movements
  • weakness when lifting or rotating the arm
  • a crackling sensation (crepitus) when moving the shoulder in certain positions

A tear from a sudden injury usually causes intense pain, and there may be a snapping sensation and immediate weakness in the upper arm1. A tear that develops slowly may start as mild pain only when you reach overhead; some tears are not painful at all but still cause weakness1.

Can a rotator cuff tear heal without surgery?

Symptoms often settle without an operation. AAOS reports that nonsurgical treatment (rest, activity changes, anti-inflammatory medication, physical therapy and, if needed, a cortisone injection) relieves pain and improves function in about 80 to 85% of patients1. On average, AAOS says, a cortisone injection relieves pain in about two-thirds of patients for at least three months, and repeated injections carry risks1.

A multicenter study from the MOON Shoulder Group followed 452 people with full-thickness tears that were not caused by an injury, all of whom started a structured physical therapy program. Fewer than 25% chose surgery over two years, and most who did decided between 6 and 12 weeks2. At 10 years, therapy had succeeded in more than 70% of patients, and scores in those who never had surgery did not decline over the decade10.

The trade-off is that an unrepaired tear can grow, and AAOS lists this among the disadvantages of nonsurgical care1. In a Norwegian study of 49 unrepaired tears rechecked after about 8.8 years, tears grew on average, often only moderately, but patients whose tears grew by 20 mm or more had worse shoulder function11.

When is rotator cuff surgery needed?

Continued pain despite nonsurgical treatment is the main reason for surgery, and a doctor may also suggest it for people who are very active or use their arms overhead for work or sports1. Other signs that surgery may be a good option include1:

  • symptoms that have lasted 6 to 12 months
  • a large tear (more than 3 cm) with good-quality surrounding tissue
  • significant weakness and loss of function in the shoulder
  • a tear caused by a recent, acute injury

Timing may matter after an injury. In a study of 206 patients with injury-related full-thickness tears, those repaired within 4 months of the injury had better shoulder scores than those repaired later12. A 2025 study of 141 patients also linked longer time to surgery with lower scores13.

Repair usually means stitching the tendon back to the upper arm bone, most often arthroscopically and without an overnight stay14. A sling is usually worn for the first 4 to 6 weeks, strengthening exercises start at 8 to 12 weeks, and most patients have functional motion and adequate strength by 4 to 6 months14. A re-tear is possible after any repair and is more likely with larger tears, though AAOS notes that people who re-tear usually do not have greater pain or decreased function14.

Physical therapy vs surgery: what do the trials show?

StudyWho was studiedWhat it found
Finnish trial, 2 years [15]180 shoulders with nontraumatic supraspinatus tears, randomized to physiotherapy alone, acromioplasty with physiotherapy, or repairShoulder scores improved in all three groups; repaired tears were smaller on follow-up imaging (4.2 mm vs 11.0 mm)
Finnish trial, about 6 years [16]150 shoulders, patients older than 55Shoulder scores in all three groups remained improved from baseline at an average of 6.2 years
Norwegian trial, 15 years [17]103 patients with full-thickness tears up to 3 cmPrimary repair gave better shoulder scores and less pain than physiotherapy; in tears treated by physiotherapy alone, average tear size grew from 16.2 to 31.6 mm

The Finnish authors concluded that conservative care is a reasonable first treatment for isolated, nontraumatic supraspinatus tears in older patients15,16. The Norwegian trial, with the longest follow-up, supports repair as the first treatment for small-to-medium tears17.

Does PRP help a rotator cuff tear?

Platelet-rich plasma (PRP) has been studied both as an injection on its own and as an add-on during surgical repair.

As an injection, compared with cortisone. A 2026 meta-analysis of 10 randomized trials with 591 adults who had rotator cuff tendinopathy or partial tears compared PRP injections with cortisone (corticosteroid) injections18. At six months, patients treated with PRP had better shoulder scores (10.8 points higher on the American Shoulder and Elbow Surgeons score and 10.7 points higher on the Constant-Murley score) and less pain, and PRP was associated with fewer adverse events18. The authors concluded that PRP may be a more durable treatment option for rotator cuff tendinopathy18.

Added during surgery. A 2022 review of 13 meta-analyses covering 1,800 patients, with follow-up of 12 to 36 months, found that using PRP during arthroscopic rotator cuff repair led to fewer re-tears, better short-term scores after surgery and better function compared with control groups, and pain scores showed short-term pain relief3. The authors concluded that PRP is effective in reducing re-tears after rotator cuff repair, improving function scores and reducing short-term pain3.

What about stem cell (BMAC) therapy for the rotator cuff?

The rotator cuff studies of stem cells described here used cells taken from bone marrow4,5.

  • Added during surgery. In a French case-controlled study, 45 patients received bone marrow concentrate during arthroscopic repair and were compared with 45 matched patients who did not. All 45 treated repairs had healed by six months, compared with 30 of 45 controls. At ten years, 87% of the treated group and 44% of the controls still had an intact rotator cuff4. Patients whose repairs later lost integrity had received fewer stem cells than those whose repairs held4. The authors concluded that the results support adding bone marrow-derived stem cells to rotator cuff repair, because of the improved healing rate and fewer re-tears over time4.
  • As an injection, without surgery. In a US randomized trial, 51 patients with high-grade partial or full-thickness supraspinatus tears received either bone marrow concentrate with platelet products (34 patients) or a home exercise program (17 patients)5. At three months, the bone marrow concentrate group reported significantly greater improvement in pain, arm function and overall shoulder rating. Their scores continued to improve through the two-year follow-up without a serious adverse event, and 73% of treated patients with before-and-after MRIs showed signs of healing5.

At our practice, physical therapy comes first. PRP, BMAC or the two combined may be considered when it has not worked. Not every patient is a candidate, and candidacy is decided at a consultation before any financial commitment. Orthobiologic procedures are performed at the Pueblo Surgery Center, a free-standing, AAAHC-accredited outpatient facility at the same address as the office. For BMAC, the marrow is drawn, processed and delivered in one visit, with light anesthesia so there is no discomfort during the harvest.

When should you see a doctor about shoulder pain?

AAOS advises that chronic shoulder and arm pain are good reasons to see a doctor, and that continuing to use a torn shoulder despite increasing pain can cause further damage1.

Patients outside the area can have the first consultation and follow-ups by telemedicine, with imaging sent by email. If you are in the Santa Barbara area, Dr. Scheinberg can examine your shoulder, review any imaging and talk through the options. See shoulder care or call (805) 682-1394.

Frequently asked questions

Short answers to the questions patients ask most.

Have a question about your own situation?

Call (805) 682-1394
Can a torn rotator cuff heal on its own?

Pain and function often improve without surgery; in one large study, physical therapy succeeded in more than 70% of people with nontraumatic full-thickness tears at 10 years10. The tear itself may still grow. In a 15-year trial, unrepaired tears grew from an average of 16.2 mm to 31.6 mm17.

Is a partial rotator cuff tear serious?

A partial tear goes only partway through the tendon, which stays attached to the bone1. Nonsurgical care is often the first line for most patients9. Tears can progress from partial to full thickness, though not all do8.

How long does it take to recover from rotator cuff surgery?

Expect several months. The arm is usually in a sling for 4 to 6 weeks, and most patients have functional motion and adequate strength by 4 to 6 months after surgery14.

Do I need an MRI for a rotator cuff tear?

X-rays usually come first and are often normal, because they do not show the rotator cuff tendons1. An MRI or ultrasound can show the location and size of a tear; the accuracy of ultrasound depends on the person performing the scan1.

Can PRP or stem cells help a rotator cuff tear?

Studies have found benefits. PRP injections gave better shoulder scores and less pain than cortisone at six months18, adding PRP or bone marrow concentrate to surgical repair was linked with fewer re-tears3,4, and bone marrow concentrate with platelet products improved pain and function more than a home exercise program5.

References

  1. 1. Aibinder WR (contributor), Mulcahey MK (reviewer). Rotator cuff tears. OrthoInfo, American Academy of Orthopaedic Surgeons. orthoinfo.aaos.org
  2. 2. Kuhn JE, Dunn WR, Sanders R, et al. Effectiveness of physical therapy in treating atraumatic full-thickness rotator cuff tears: a multicenter prospective cohort study. J Shoulder Elbow Surg. 2013;22(10):1371-1379. PubMed
  3. 3. Ahmad Z, Ang S, Rushton N, et al. Platelet-rich plasma augmentation of arthroscopic rotator cuff repair lowers retear rates and improves short-term postoperative functional outcome scores: a systematic review of meta-analyses. Arthrosc Sports Med Rehabil. 2022;4(2):e823-e833. PubMed
  4. 4. Hernigou P, Flouzat Lachaniette CH, Delambre J, et al. Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study. Int Orthop. 2014;38(9):1811-1818. PubMed
  5. 5. Centeno CJ, Fausel Z, Dodson E, et al. Percutaneous bone marrow concentrate and platelet products versus exercise therapy for the treatment of rotator cuff tears: a randomized controlled, crossover trial with 2-year follow-up. BMC Musculoskelet Disord. 2024;25(1):392. PubMed
  6. 6. Minagawa H, Yamamoto N, Abe H, et al. Prevalence of symptomatic and asymptomatic rotator cuff tears in the general population: from mass-screening in one village. J Orthop. 2013;10(1):8-12. PubMed
  7. 7. Teunis T, Lubberts B, Reilly BT, Ring D. A systematic review and pooled analysis of the prevalence of rotator cuff disease with increasing age. J Shoulder Elbow Surg. 2014;23(12):1913-1921. PubMed
  8. 8. Bedi A, Bishop J, Keener J, et al. Rotator cuff tears. Nat Rev Dis Primers. 2024;10(1):8. PubMed
  9. 9. Plancher KD, Shanmugam J, Briggs K, Petterson SC. Diagnosis and management of partial thickness rotator cuff tears: a comprehensive review. J Am Acad Orthop Surg. 2021;29(24):1031-1043. PubMed
  10. 10. Kuhn JE, Dunn WR, Sanders R, et al. The predictors of surgery for symptomatic, atraumatic full-thickness rotator cuff tears change over time: ten-year outcomes of the MOON Shoulder Prospective Cohort. J Bone Joint Surg Am. 2024;106(17):1563-1572. PubMed
  11. 11. Moosmayer S, Gärtner AV, Tariq R. The natural course of nonoperatively treated rotator cuff tears: an 8.8-year follow-up of tear anatomy and clinical outcome in 49 patients. J Shoulder Elbow Surg. 2017;26(4):627-634. PubMed
  12. 12. Gutman MJ, Joyce CD, Patel MS, et al. Early repair of traumatic rotator cuff tears improves functional outcomes. J Shoulder Elbow Surg. 2021;30(11):2475-2483. PubMed
  13. 13. B Pohl N, Curry M, Romiyo V, et al. Timing of surgical repair for traumatic rotator cuff tears. Eur J Orthop Surg Traumatol. 2025;35(1):272. PubMed
  14. 14. Aibinder WR (contributor), Mulcahey MK (reviewer). Rotator cuff tears: surgical treatment options. OrthoInfo, American Academy of Orthopaedic Surgeons. orthoinfo.aaos.org
  15. 15. Kukkonen J, Joukainen A, Lehtinen J, et al. Treatment of nontraumatic rotator cuff tears: a randomized controlled trial with two years of clinical and imaging follow-up. J Bone Joint Surg Am. 2015;97(21):1729-1737. PubMed
  16. 16. Kukkonen J, Ryösä A, Joukainen A, et al. Operative versus conservative treatment of small, nontraumatic supraspinatus tears in patients older than 55 years: over 5-year follow-up of a randomized controlled trial. J Shoulder Elbow Surg. 2021;30(11):2455-2464. PubMed
  17. 17. Moosmayer S, Lund G, Seljom US, et al. Fifteen-year results of a comparative analysis of tendon repair versus physiotherapy for small-to-medium-sized rotator cuff tears: a concise follow-up of previous reports. J Bone Joint Surg Am. 2024;106(19):1785-1796. PubMed
  18. 18. Yuwarungsikul C, Phisalaphong K, Thamrongskulsiri N, et al. Platelet-rich plasma provides modest but durable functional benefit over corticosteroid for rotator cuff tendinopathy: a systematic review and meta-analysis of randomized controlled trials. Knee Surg Sports Traumatol Arthrosc. 2026;34(8):2937-2950. PubMed

Reviewed by Dr. Richard Scheinberg, MD, a board-certified orthopedic surgeon in Santa Barbara with 40 years of surgical experience.